Structure of PDB 8g6e Chain a

Receptor sequence
>8g6ea (length=215) Species: 5843 (Plasmodium falciparum NF54) [Search protein sequence]
GFKRWYPYIDNGGTVIGLTGKDYVILAADTRLSLSYSIYTRFCPKISKLT
DKCIIGSSGMQSDIKTLHSLLQKKIQLFVLEHSHYPDIHVIARLLCVILY
SRRFFPYYAFNILAGVDENNKGVLYNYDSVGSYCEATHSCVGSGSQLILP
ILDNRVEQKNQLIKNTNFNLGDDINFVKDAITSATERDIYTGDKTLIYVI
DKMGINVNTLDLKQD
3D structure
PDB8g6e Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium proteasome inhibitors
Chaina
Resolution2.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YRE a F135 D153 S154 S157 C159 F110 D128 S129 S132 C134
Gene Ontology
Biological Process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005839 proteasome core complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8g6e, PDBe:8g6e, PDBj:8g6e
PDBsum8g6e
PubMed38097652
UniProtA0A2I0BU46

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