Structure of PDB 8g0e Chain a

Receptor sequence
>8g0ea (length=234) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
IHVGHHTLVFELFGMTFNGDTILATAVTAVIVIALAFYLRAKVTSTGVPS
GVQLFWEALTIQMRQQIEGSIGMKIAPFVLPLSVTIFVFILISNWLAVLP
LQYGGGAAAELYKAPASDINFVLALALFVFVCYHAAGIWRRGIVGHPIKV
VKGHVAFLAPINIVEELAKPISLALRLFGNIFAGGILVALIAMFPWYIQW
FPNAVWKTFDLFVGLIQAFIFSLLTILYFSQSME
3D structure
PDB8g0e Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines.
Chaina
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YGR a P172 I173 V176 P160 I161 V164
BS02 YGR a F213 W218 F221 F201 W206 F209
Gene Ontology
Molecular Function
GO:0015078 proton transmembrane transporter activity
GO:0016787 hydrolase activity
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
Biological Process
GO:0006754 ATP biosynthetic process
GO:0015986 proton motive force-driven ATP synthesis
GO:0042777 proton motive force-driven plasma membrane ATP synthesis
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8g0e, PDBe:8g0e, PDBj:8g0e
PDBsum8g0e
PubMed37377118
UniProtA0R206

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