Structure of PDB 8g0a Chain a

Receptor sequence
>8g0aa (length=235) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
AIHVGHHTLVFELFGMTFNGDTILATAVTAVIVIALAFYLRAKVTSTGVP
SGVQLFWEALTIQMRQQIEGSIGMKIAPFVLPLSVTIFVFILISNWLAVL
PLQYGGGAAAELYKAPASDINFVLALALFVFVCYHAAGIWRRGIVGHPIK
VVKGHVAFLAPINIVEELAKPISLALRLFGNIFAGGILVALIAMFPWYIQ
WFPNAVWKTFDLFVGLIQAFIFSLLTILYFSQSME
3D structure
PDB8g0a Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines.
Chaina
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SQC a H166 N174 E177 K181 R188 Y240 H155 N163 E166 K170 R177 Y229
Gene Ontology
Molecular Function
GO:0015078 proton transmembrane transporter activity
GO:0016787 hydrolase activity
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
Biological Process
GO:0006754 ATP biosynthetic process
GO:0015986 proton motive force-driven ATP synthesis
GO:0042777 proton motive force-driven plasma membrane ATP synthesis
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8g0a, PDBe:8g0a, PDBj:8g0a
PDBsum8g0a
PubMed37377118
UniProtA0R206

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