Structure of PDB 8ccs Chain a

Receptor sequence

>8ccsa (length=102) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]

VNVPKTRKTYCKGKTCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFG
GQTKPVFHKKAKTTKKVVLRLECVKCKTRAQLTLKRCKHFELGGEKKQKG
QA

3D structure

PDB

8ccs Cryo-EM analysis of eukaryotic ribosome translocation intermediates

Chain

Resolution

1.97 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	a	V2 N3 P5 R8 K9 T10 Y11 K13 K19 H20 Y28 A30 S34 F36 A37 Q38 G39 R41 R42 R45 K46 G49 F50 G51 G52 Q53 T54 K55 P56 V57 F58 K60 K61 A62 K63 T65 K66 K67 V69 R80 Q82 L83 T84 K86 R87 C88 K89 K97 K98 K100	V1 N2 P4 R7 K8 T9 Y10 K12 K18 H19 Y27 A29 S33 F35 A36 Q37 G38 R40 R41 R44 K45 G48 F49 G50 G51 Q52 T53 K54 P55 V56 F57 K59 K60 A61 K62 T64 K65 K66 V68 R79 Q81 L82 T83 K85 R86 C87 K88 K96 K97 K99
BS02	rna	a	Y43 K55 P56 F58	Y42 K54 P55 F57
BS03	ZN	a	C12 C17 C74 C77	C11 C16 C73 C76

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0008270	zinc ion binding

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0044391	ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:8ccs, PDBe:8ccs, PDBj:8ccs
PDBsum	8ccs
PubMed	38030725
UniProt	P0CX27\|RL44A_YEAST Large ribosomal subunit protein eL42A (Gene Name=RPL42A)