Structure of PDB 7ezj Chain a

Receptor sequence
>7ezja (length=199) Species: 9606 (Homo sapiens) [Search protein sequence]
EFIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQ
IKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPAS
HLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSC
VGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYRE
3D structure
PDB7ezj Deciphering the mechanism of p73 recognition of p53 response elements using the crystal structure of p73-DNA complexes and computational studies.
Chaina
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna a A137 K138 A25 K26
BS02 dna a S261 R293 C295 A296 R300 S149 R181 C183 A184 R188
BS03 ZN a C194 H197 C258 C262 C82 H85 C146 C150
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ezj, PDBe:7ezj, PDBj:7ezj
PDBsum7ezj
PubMed35217090
UniProtO15350|P73_HUMAN Tumor protein p73 (Gene Name=TP73)

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