Structure of PDB 6xzb Chain Z2

Receptor sequence
>6xzbZ2 (length=58) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
AKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAIRGMINAV
SFMVKVEE
3D structure
PDB6xzb Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome.
ChainZ2
Resolution2.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna Z2 S12 I14 G15 P18 K19 A22 T23 L25 G26 G28 R30 I32 R38 A43 G46 M47 S11 I13 G14 P17 K18 A21 T22 L24 G25 G27 R29 I31 R37 A42 G45 M46
BS02 rna Z2 H20 F53 H19 F52
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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External links
PDB RCSB:6xzb, PDBe:6xzb, PDBj:6xzb
PDBsum6xzb
PubMed32144191
UniProtP0AG51|RL30_ECOLI Large ribosomal subunit protein uL30 (Gene Name=rpmD)

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