Structure of PDB 8ud9 Chain Z

Receptor sequence
>8ud9Z (length=201) Species: 9606 (Homo sapiens) [Search protein sequence]
TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAA
DCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTM
ICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVE
QAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYS
G
3D structure
PDB8ud9 Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium proteasome inhibitors
ChainZ
Resolution2.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.25.1: proteasome endopeptidase complex.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YRE Z T1 A20 T21 V31 M45 G47 G48 A49 T1 A20 T21 V31 M45 G47 G48 A49
Gene Ontology
Molecular Function
GO:0004298 threonine-type endopeptidase activity
Biological Process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0005839 proteasome core complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ud9, PDBe:8ud9, PDBj:8ud9
PDBsum8ud9
PubMed38097652
UniProtP28074|PSB5_HUMAN Proteasome subunit beta type-5 (Gene Name=PSMB5)

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