Structure of PDB 8e74 Chain Z

Receptor sequence
>8e74Z (length=122) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
DPAAALKAELRSKPGDWYVVHSYAGYENKVKANLETRVQNLDVGDYIFQV
EVPTEEVTEIKNGQRKQVNRKVLPGYILVRMDLTDDSWAAVRNTPGVTGF
VGATSRPSALALDDVVKFLLPR
3D structure
PDB8e74 Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
ChainZ
Resolution2.94 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna Z Y55 W120 R124 Y23 W88 R92
BS02 dna Z Y58 K61 Y26 K29
Gene Ontology
Biological Process
GO:0006353 DNA-templated transcription termination
GO:0006354 DNA-templated transcription elongation
GO:0031564 transcription antitermination
GO:0032784 regulation of DNA-templated transcription elongation
GO:0140673 transcription elongation-coupled chromatin remodeling
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8e74, PDBe:8e74, PDBj:8e74
PDBsum8e74
PubMed37116494
UniProtP9WIU9|NUSG_MYCTU Transcription termination/antitermination protein NusG (Gene Name=nusG)

[Back to BioLiP]