Structure of PDB 8b4b Chain Z

Receptor sequence
>8b4bZ (length=110) Species: 666 (Vibrio cholerae) [Search protein sequence]
MKFILAEKFTFDPLSNTLIDKEDSEEIIRLGSNESRILWLLAQRPNEVIS
RNDLHDFVWREQGFEVDDSSLTQAISTLRKMLKDSTKSPQYVKTVPKRGY
QLIARVETVE
3D structure
PDB8b4b ToxR activates the Vibrio cholerae virulence genes by tethering DNA to the membrane through versatile binding to multiple sites.
ChainZ
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna Z W64 V71 S74 Q78 K92 W59 V66 S69 Q73 K87
BS02 dna Z T77 Q78 S81 K85 T91 T99 K102 Y105 T72 Q73 S76 K80 T86 T94 K97 Y100
Gene Ontology
Biological Process
GO:0000160 phosphorelay signal transduction system
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8b4b, PDBe:8b4b, PDBj:8b4b
PDBsum8b4b
PubMed37428913
UniProtP15795|TOXR_VIBCH Cholera toxin transcriptional activator (Gene Name=toxR)

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