Structure of PDB 7syp Chain Z

Receptor sequence

>7sypZ (length=124) Species: 9986 (Oryctolagus cuniculus)

TVTIRTRKFMTNRLLQRKQMVIDVLHPGKATVPKTEIREKLAKMYKTTPD
VIFVFGFRTHFGGGKTTGFGMIYDSLDYAKKNEPKHRLARHGLYEKKKTS
RKQRKERKNRMKKVRGTAKANVGA

3D structure

• PDB: 7syp Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
• Chain: Z
• Resolution: 4.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Z	R8 K11 F12 T14 K32 A33 T34 P36 G59 F60 R61 T62 H63 F64 G66 H89 R93 S103 R104 K105 R107 K108 E109 K111 N112 K115 K116 G119 T120	R5 K8 F9 T11 K29 A30 T31 P33 G56 F57 R58 T59 H60 F61 G63 H86 R90 S100 R101 K102 R104 K105 E106 K108 N109 K112 K113 G116 T117

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0044391 ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7syp, PDBe:7syp, PDBj:7syp
• PDBsum: 7syp
• PubMed: 35822879
• UniProt: G1T3D8