Structure of PDB 5l5s Chain Z

Receptor sequence
>5l5sZ (length=222) Species: 9606,559292 [Search protein sequence]
QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNI
VMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYSR
RFFPYYVYNIIAGLDEDGKGAVYSFDPVGSYQREQCRAGGAAASLIMPFL
DNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGD
GLEILIVTKDGVRKEFYELKRD
3D structure
PDB5l5s A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i.
ChainZ
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.25.1: proteasome endopeptidase complex.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 39V Z S124 F125 S124 F125
BS02 MG Z T192 V198 T192 V198
Gene Ontology
Biological Process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0005839 proteasome core complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5l5s, PDBe:5l5s, PDBj:5l5s
PDBsum5l5s
PubMed27789522
UniProtP20618|PSB1_HUMAN Proteasome subunit beta type-1 (Gene Name=PSMB1);
P23724|PSB6_YEAST Proteasome subunit beta type-6 (Gene Name=PRE7)

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