Structure of PDB 5a2q Chain Z

Receptor sequence
>5a2qZ (length=72) Species: 9606 (Homo sapiens) [Search protein sequence]
DKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQEL
LSKGLIKLVSKHRAQVIYTRNT
3D structure
PDB5a2q Cryo-Em Structure of Hepatitis C Virus Ires Bound to the Human Ribosome at 3.9 Angstrom Resolution
ChainZ
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna Z K43 L44 R80 G81 S82 R85 K102 H103 R104 K2 L3 R39 G40 S41 R44 K61 H62 R63
BS02 rna Z E61 N64 Y65 E75 R76 E20 N23 Y24 E34 R35
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006364 rRNA processing
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0014069 postsynaptic density
GO:0015935 small ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0045202 synapse
GO:0070062 extracellular exosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Cellular Component
External links
PDB RCSB:5a2q, PDBe:5a2q, PDBj:5a2q
PDBsum5a2q
PubMed26155016
UniProtP62851|RS25_HUMAN Small ribosomal subunit protein eS25 (Gene Name=RPS25)

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