Structure of PDB 8olu Chain Y

Receptor sequence
>8oluY (length=206) Species: 5689 (Leishmania tarentolae) [Search protein sequence]
MAETAIAFRCKDYVMVAAAGLNAFYYIKITDAEDKITQLDTHQLVACTGE
NGPRVNFTEYIKCNLALNRMRQHGRHSSCESTANFMRNCLASAIRSREGA
YQVNCLFAGYDTPVSEDDDGVVGPQLFYMDYLGTLQAVPYGCHGYGACFV
TALLDRLWRPDLSQQEGLELMQKCCDEVKRRVIISNSYFFVKAVTKNGVE
VITAVH
3D structure
PDB8olu Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors.
ChainY
Resolution2.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VYW Y F24 I29 F24 I29
Gene Ontology
Biological Process
GO:0010498 proteasomal protein catabolic process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005839 proteasome core complex
GO:0019774 proteasome core complex, beta-subunit complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8olu, PDBe:8olu, PDBj:8olu
PDBsum8olu
PubMed37506194
UniProtA0A640KTY7

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