Structure of PDB 8fyw Chain Y

Receptor sequence
>8fywY (length=519) Species: 10804 (adeno-associated virus 2) [Search protein sequence]
GADGVGNSSGNWHCDSTWMGDRVITTSTRTWALPTYNNHLYKQISSQSGA
SNDNHYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLNFKLF
NIQVKEVTQNDGTTTIANNLTSTVQVFTDSEYQLPYVLGSAHQGCLPPFP
ADVFMVPQYGYLTLNNGSQAVGRSSFYCLEYFPSQMLRTGNNFTFSYTFE
DVPFHSSYAHSQSLDRLMNPLIDQYLYYLSRTNTPSGTTTQSRLQFSQAG
ASDIRDQSRNWLPGPCYRQQRVSKTSADNNNSEYSWTGATKYHLNGRDSL
VNPGPAMASHKDDEEKFFPQSGVLIFGKQGSEKTNVDIEKVMITDEEEIR
TTNPVATEQYGSVSTNLQRGNRQAATADVNTQGVLPGMVWQDRDVYLQGP
IWAKIPHTDGHFHPSPLMGGFGLKHPPPQILIKNTPVPANPSTTFSAAKF
ASFITQYSTGQVSVEIEWELQKENSKRWNPEIQYTSNYNKSVNVDFTVDT
NGVYSEPRPIGTRYLTRNL
3D structure
PDB8fyw Cryo-EM Structure of genome containing AAV2
ChainY
Resolution2.84 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DA Y H629 P630 S631 G638 H413 P414 S415 G422
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0019062 virion attachment to host cell
GO:0046718 symbiont entry into host cell
GO:0075512 clathrin-dependent endocytosis of virus by host cell
GO:0140267 symbiont entry into host cell via permeabilization of host membrane
Cellular Component
GO:0019028 viral capsid
GO:0039615 T=1 icosahedral viral capsid
GO:0042025 host cell nucleus
GO:0044196 host cell nucleolus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8fyw, PDBe:8fyw, PDBj:8fyw
PDBsum8fyw
PubMed
UniProtP03135|CAPSD_AAV2S Capsid protein VP1 (Gene Name=VP1)

[Back to BioLiP]