Structure of PDB 8c8h Chain Y

Receptor sequence
>8c8hY (length=539) Species: 502057 (Vaccinia virus GLV-1h68) [Search protein sequence]
KSHAAYIDYALRRTTNMPVEMMGSDVVRLKDYQHFVARVFLGLDSMHSLL
LFHETGVGKTMTTVYILKHLKDIYTNWAIILLVKKALIEDPWMNTILRYA
PEITKDCIFINYDDQNFRNKFFTNIKTINSKSRICVIIDECHNFISKSLI
KEDGKIRPTRSVYNFLSKTIALKNHKMICLSATPIVNSVQEFTMLVNLLR
PGSLQHQSLFENKRLVDEKELVSKLGGLCSYIVNNEFSIFDDVEGSASFA
KKTVLMRYVNMSKKQEEIYQKAKLAEIKTGISSFRILRRMATTFTFNDFK
NSLRDREFSKSALDTFKKGELLKGDASAADISLFTELKEKSVKFIDVCLG
ILASHGKCLVFEPFQSGIEILLLYFKVFGISNIEFSSRTKDTRIKAVAEF
NQESNTNGECIKTCVFSSSGGEGISFFSINDIFILDMTWNEASLRQIVGR
AIRLNSHVLTPPERRYVNVHFIMARLSNGMPTVDEDLFEIIQSKSKEFVQ
LFRVFKHTSLEWIHANEKDFSPIDNESGWKTLVSRAIDL
3D structure
PDB8c8h Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes.
ChainY
Resolution3.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna Y R120 F124 K153 K157 I158 R159 R162 S163 N166 K170 K175 H208 R118 F122 K151 K155 I156 R157 R160 S161 N164 K168 K173 H206
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0017111 ribonucleoside triphosphate phosphatase activity
GO:0140658 ATP-dependent chromatin remodeler activity
Biological Process
GO:0006338 chromatin remodeling
GO:0006351 DNA-templated transcription
Cellular Component
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8c8h, PDBe:8c8h, PDBj:8c8h
PDBsum8c8h
PubMed
UniProtP05807|NTP1_VACCW Nucleoside triphosphatase I (Gene Name=OPG123)

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