Structure of PDB 7syr Chain Y

Receptor sequence

>7syrY (length=141) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

GKCRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIV
LEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVL
VAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPR

3D structure

PDB

7syr Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.

Chain

Resolution

3.6 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Y	G2 R5 R8 T9 R11 K12 L13 H16 R17 R18 Q20 K21 W22 H23 D24 K28 L36 A44 S45 H46 A47 K48 K60 Q61 N63 S64 R67 K68 P86 D88 G104 G106 R107 K108 H110 V112 G113 D114 K124 S129 K137	G1 R4 R7 T8 R10 K11 L12 H15 R16 R17 Q19 K20 W21 H22 D23 K27 L35 A43 S44 H45 A46 K47 K59 Q60 N62 S63 R66 K67 P85 D87 G103 G105 R106 K107 H109 V111 G112 D113 K123 S128 K136

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005791	rough endoplasmic reticulum
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0022626	cytosolic ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:7syr, PDBe:7syr, PDBj:7syr
PDBsum	7syr
PubMed	35822879
UniProt	G1SZ47\|RS23_RABIT Small ribosomal subunit protein uS12 (Gene Name=RPS23)