Structure of PDB 7sym Chain Y

Receptor sequence

>7symY (length=141) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

GKCRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIV
LEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVL
VAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPR

3D structure

PDB

7sym Comprehensive structural overview of the HCV IRES-mediated translation initiation pathway

Chain

Resolution

4.8 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Y	G2 K3 C4 R5 G6 R8 T9 R11 K12 H16 R17 R18 Q20 H23 D24 K25 K28 L36 G43 A44 S45 H46 A47 K48 Q61 N63 S64 I66 R67 K68 K76 P86 N87 D88 L101 G104 F105 G106 R107 K108 A111 V112 G113 D114 R119 K124 S129 K137 K138	G1 K2 C3 R4 G5 R7 T8 R10 K11 H15 R16 R17 Q19 H22 D23 K24 K27 L35 G42 A43 S44 H45 A46 K47 Q60 N62 S63 I65 R66 K67 K75 P85 N86 D87 L100 G103 F104 G105 R106 K107 A110 V111 G112 D113 R118 K123 S128 K136 K137

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005791	rough endoplasmic reticulum
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0022626	cytosolic ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:7sym, PDBe:7sym, PDBj:7sym
PDBsum	7sym
PubMed
UniProt	G1SZ47\|RS23_RABIT Small ribosomal subunit protein uS12 (Gene Name=RPS23)