Structure of PDB 7rh7 Chain Y

Receptor sequence
>7rh7Y (length=382) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
GQPTDAELAEMSREELVKLGGKIDGVETIFKEPRWPVPGTKAEKRTERLV
AYWLMLGGLSGLALLLVFLFWPWEYQPFGSEGEFLYSLATPLYGLTFGLS
ILSIGIGAVLFQKKFIPEEISVQDRHDGRSPEVHRKTVAANLTDALEGST
LKRRKVIGLSLGIGLGAFGAGTLVAFIGGLIKNPWKPVVPTAEGKKAVLW
TSGWTPRFKGETIYLARATGRPGESPFVKMRPEDIDAGGMETVFPWRESD
GDGTTVESEHKLTEIAMGVRNPVMLIRIKPADMHRVIKRKGQESFNFGEL
FAYTKVCSHLGCPSSLYEQQTYRILCPCHQSQFDALEFAKPIFGPAARAL
AQLPITIDEDGYLVANGDFVEPVGPAFWERKS
3D structure
PDB7rh7 Structure of mycobacterial CIII 2 CIV 2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203).
ChainY
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MQ9 Y F207 T211 A214 F215 F168 T172 A175 F176
BS02 FES Y C346 H348 C351 C365 H368 C307 H309 C312 C326 H329
BS03 9YF Y W224 W239 W417 E418 W185 W200 W378 E379
BS04 9YF Y L212 V213 I216 G217 G218 I220 N222 L173 V174 I177 G178 G179 I181 N183
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Cellular Component
GO:0005886 plasma membrane

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Molecular Function

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Cellular Component
External links
PDB RCSB:7rh7, PDBe:7rh7, PDBj:7rh7
PDBsum7rh7
PubMed34590581
UniProtI7GD61

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