Structure of PDB 6ruv Chain Y

Receptor sequence
>6ruvY (length=215) Species: 9606 (Homo sapiens) [Search protein sequence]
GVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTH
ICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRK
FDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQ
RLCTPLLPKYPPTVSMVEGQGEKNVTFWGRPLPRCEELQGQKLVVEEKRP
CLHVPACKDPEEEEL
3D structure
PDB6ruv Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
ChainY
Resolution6.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FUC Y T272 P313 T18 P59
BS02 BGC Y V271 C312 P313 V17 C58 P59
BS03 MAN Y W321 R346 W67 R92
BS04 MAN Y S381 W382 S127 W128
BS05 MAN Y T387 W388 R401 T133 W134 R147
BS06 MAN Y E384 W385 E130 W131
BS07 MAN Y G259 W260 R282 G5 W6 R28
BS08 MAN Y G261 P262 W263 G7 P8 W9
External links
PDB RCSB:6ruv, PDBe:6ruv, PDBj:6ruv
PDBsum6ruv
PubMed31507604
UniProtP27918|PROP_HUMAN Properdin (Gene Name=CFP)

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