Structure of PDB 6p5n Chain Y

Receptor sequence

>6p5nY (length=141) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

GKCRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIV
LEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVL
VAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPR

3D structure

PDB

6p5n The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.

Chain

Resolution

3.2 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Y	G2 K3 R5 G6 R8 T9 R11 K12 R17 R18 Q20 W22 H23 D24 K28 L36 K37 A44 S45 K48 K60 N63 S64 A65 I66 R67 K68 I75 K76 P86 D88 G89 G104 G106 R107 K108 H110 V112 G113 D114 K124 S129 L131 A132 K137	G1 K2 R4 G5 R7 T8 R10 K11 R16 R17 Q19 W21 H22 D23 K27 L35 K36 A43 S44 K47 K59 N62 S63 A64 I65 R66 K67 I74 K75 P85 D87 G88 G103 G105 R106 K107 H109 V111 G112 D113 K123 S128 L130 A131 K136

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005791	rough endoplasmic reticulum
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0022626	cytosolic ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:6p5n, PDBe:6p5n, PDBj:6p5n
PDBsum	6p5n
PubMed	31609474
UniProt	G1SZ47\|RS23_RABIT Small ribosomal subunit protein uS12 (Gene Name=RPS23)