Structure of PDB 6gej Chain Y

Receptor sequence
>6gejY (length=447) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
LKSLSLIAAHSHITGLGLDENLQPRPTSEGMVGQLQARRAAGVILKMVQN
GTIAGRAVLVAGPPSTGKTALAMGVSQSLGKDVPFTAIAGSEIFSLELSK
TEALTQAFRKSIGIKIKEETELIEGEVVEIQIDRSITGGHKQGKLTIKTT
DMETIYELGNKMIDGLTKEKVLAGDVISIDKASGKITKLGRSFARSRDYD
AMGADTRFVQCPEGELQKRKTVVHTVSLHEIDVINSRTQGFLALFTGDTG
EIRSEVRDQINTKVAEWKEEGKAEIVPGVLFIDEVHMLDIECFSFINRAL
EDEFAPIVMMATNRGVSKTRGTNYKSPHGLPLDLLDRSIIITTKSYNEQE
IKTILSIRAQEEEVELSSDALDLLTKTGVETSLRYSSNLISVAQQIAMKR
KNNTVEVEDVKRAYLLFLDSARSVKYVQENESQYIDDQGNVQISIAK
3D structure
PDB6gej Structure and dynamics of the yeast SWR1-nucleosome complex.
ChainY
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP Y H23 M44 V45 P77 S78 G80 T82 A83 Y359 I367 R397 H10 M31 V32 P64 S65 G67 T69 A70 Y346 I354 R384
BS02 MG Y T82 D296 T69 D283
Gene Ontology
Molecular Function
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0043138 3'-5' DNA helicase activity
GO:0043139 5'-3' DNA helicase activity
Biological Process
GO:0000492 box C/D snoRNP assembly
GO:0006281 DNA repair
GO:0006325 chromatin organization
GO:0006338 chromatin remodeling
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006364 rRNA processing
GO:0032508 DNA duplex unwinding
GO:0050821 protein stabilization
Cellular Component
GO:0000785 chromatin
GO:0000812 Swr1 complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0031011 Ino80 complex
GO:0035267 NuA4 histone acetyltransferase complex
GO:0097255 R2TP complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6gej, PDBe:6gej, PDBj:6gej
PDBsum6gej
PubMed30309918
UniProtQ12464|RUVB2_YEAST RuvB-like protein 2 (Gene Name=RVB2)

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