Structure of PDB 6fy3 Chain Y

Receptor sequence

>6fy3Y (length=202) Species: 9606 (Homo sapiens) [Search protein sequence]

NFMLTQPHSVSESPGKTVTISCTRSSGSIASDYVQWYQQRPGSSPTTVIY
EDNQRPSGVPDRFSGSIDSSSNSASLTISGLKTEDEADYYCQSYDMTNHN
WVFGGGTKLTVLGQPKAAPSVTLFPATLVCLISDFYPGAVTVAWKADSSP
VKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEK
TV

3D structure

PDB

6fy3 Common helical V1V2 conformations of HIV-1 Envelope expose the alpha 4 beta 7 binding site on intact virions.

Chain

Resolution

2.6 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	Y	A30A S30B Y32 D51 Y91 M93 H95A	A30 S31 Y33 D52 Y94 M96 H99
BS02	peptide	Y	S22 T24 S26 G28 S67 S68 N69	S21 T23 S25 G27 S70 S71 N72

External links

PDB	RCSB:6fy3, PDBe:6fy3, PDBj:6fy3
PDBsum	6fy3
PubMed	30367034

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