Structure of PDB 5zwn Chain Y

Receptor sequence
>5zwnY (length=196) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
MSTPAAEQRKLVEQLMGPKICKSYLVGECPYDLFQGTKQSLGKCPQMHLT
KHKIQYEREVKQGKTFPEFEREYLAILSRFVNECNGQISVALQNLKHTAE
ERMKIQQVTEELDVLDVRIGLMKLQELISKRKEVAKRVRNITENVGQSAQ
QKLQVCEVCGAYLSRLDTDRRLADHFLGKIHLGYVKMREDYDRLMK
3D structure
PDB5zwn Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
ChainY
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna Y D212 R216 D167 R171
BS02 rna Y S5 T6 Y207 R216 D219 H220 K224 S2 T3 Y162 R171 D174 H175 K179
BS03 ZN Y C201 H220 H226 C156 H175 H181
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0008270 zinc ion binding
Biological Process
GO:0000395 mRNA 5'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006376 mRNA splice site recognition
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000243 commitment complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005685 U1 snRNP
GO:0005829 cytosol
GO:0071004 U2-type prespliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5zwn, PDBe:5zwn, PDBj:5zwn
PDBsum5zwn
PubMed29794219
UniProtQ07508|LUC7_YEAST Protein LUC7 (Gene Name=LUC7)

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