Structure of PDB 5yj1 Chain Y

Receptor sequence
>5yj1Y (length=93) Species: 10090 (Mus musculus) [Search protein sequence]
GPTSLCCKQCQETEITTKNEIFSLSHETLTVYKASNLNLIGRPSTVHSWF
PGYAWTIAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLP
3D structure
PDB5yj1 Structural basis of thalidomide enantiomer binding to cereblon
ChainY
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6EL Y H381 S382 W383 W389 W403 F405 H47 S48 W49 W55 W69 F71 MOAD: Kd=50.3uM
BS02 ZN Y C326 C329 C394 C397 C7 C10 C60 C63
External links
PDB RCSB:5yj1, PDBe:5yj1, PDBj:5yj1
PDBsum5yj1
PubMed29358579
UniProtQ8C7D2|CRBN_MOUSE Protein cereblon (Gene Name=Crbn)

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