Structure of PDB 5fgd Chain Y

Receptor sequence
>5fgdY (length=216) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
IALGATTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMA
GGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLS
MGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKW
DLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGEL
FWKVKEEEGSFNNVIG
3D structure
PDB5fgd A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
ChainY
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A1 D17 R19 K33 G47 S131 D168 S171
Catalytic site (residue number reindexed from 1) A5 D21 R23 K37 G51 S135 D172 S175
Enzyme Commision number 3.4.25.1: proteasome endopeptidase complex.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG Y A165 D168 A169 A169 D172 A173
Gene Ontology
Molecular Function
GO:0004298 threonine-type endopeptidase activity
Biological Process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0005839 proteasome core complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5fgd, PDBe:5fgd, PDBj:5fgd
PDBsum5fgd
PubMed26964885
UniProtP30656|PSB5_YEAST Proteasome subunit beta type-5 (Gene Name=PRE2)

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