Structure of PDB 7nwh Chain XX

Receptor sequence
>7nwhXX (length=141) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]
GKCRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIV
LEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVL
VAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPR
3D structure
PDB7nwh Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA.
ChainXX
Resolution4.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna XX G2 K3 R5 R8 K12 R17 R18 Q20 W22 K37 S45 K48 N63 I66 R67 N87 G106 R107 K108 V112 R119 S129 K137 G1 K2 R4 R7 K11 R16 R17 Q19 W21 K36 S44 K47 N62 I65 R66 N86 G105 R106 K107 V111 R118 S128 K136
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005791 rough endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7nwh, PDBe:7nwh, PDBj:7nwh
PDBsum7nwh
PubMed34157102
UniProtG1SZ47|RS23_RABIT Small ribosomal subunit protein uS12 (Gene Name=RPS23)

[Back to BioLiP]