Structure of PDB 4zsn Chain XM

Receptor sequence

>4zsnXM (length=118) Species: 300852 (Thermus thermophilus HB8)

ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEA
EVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQ
RTRTNARTRKGPRKTVAG

3D structure

• PDB: 4zsn Mechanism of endonuclease cleavage by the HigB toxin.
• Chain: XM
• Resolution: 3.6 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	XM	K13 V17 Y21 Y23 G24 I25 G26 K27 A28 R29 N77 Y87 R88 R91 L96 P97 V98 R99 G100 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 K115 T116 V117	K12 V16 Y20 Y22 G23 I24 G25 K26 A27 R28 N76 Y86 R87 R90 L95 P96 V97 R98 G99 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 K114 T115 V116
BS02	rna	XM	M82 R93	M81 R92
BS03	MG	XM	T20 I22 I25 G26	T19 I21 I24 G25

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4zsn, PDBe:4zsn, PDBj:4zsn
• PDBsum: 4zsn
• PubMed: 27378776
• UniProt: P80377|RS13_THET8 Small ribosomal subunit protein uS13 (Gene Name=rpsM)