Structure of PDB 4lsk Chain XM

Receptor sequence

>4lskXM (length=121) Species: 300852 (Thermus thermophilus HB8)

ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEA
EVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQ
RTRTNARTRKGPRKTVAGKKK

3D structure

• PDB: 4lsk Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
• Chain: XM
• Resolution: 3.48001 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	XM	R14 V17 Y21 Y23 G24 I25 G26 A28 R29 R44 V74 N77 Y87 R88 H92 P97 V98 R99 Q101 R102 T103 R104 N106 A107 R108 T109 K111 R114 K115 T116 K121	R13 V16 Y20 Y22 G23 I24 G25 A27 R28 R43 V73 N76 Y86 R87 H91 P96 V97 R98 Q100 R101 T102 R103 N105 A106 R107 T108 K110 R113 K114 T115 K120
BS02	rna	XM	A118 G119	A117 G118
BS03	MG	XM	G100 Q101	G99 Q100

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4lsk, PDBe:4lsk, PDBj:4lsk
• PDBsum: 4lsk
• PubMed: 25128388
• UniProt: P80377|RS13_THET8 Small ribosomal subunit protein uS13 (Gene Name=rpsM)