Structure of PDB 8g6e Chain X

Receptor sequence
>8g6eX (length=210) Species: 5843 (Plasmodium falciparum NF54) [Search protein sequence]
GSIYNYNGGCVLGMSGSNCVAIACDLRLGANTFTTVSTKFSKIFKMNNNV
YVGLSGLATDIQTLYEILRYRVNLYEVRQDAEMDVECFANMLSSILYSNR
FSPYFVNPIVVGFKLKHYKVNYEPYLTAYDLIGAKCETRDFVVNGVTSEQ
LFGMCESLYVKDQDENGLFETISQCLLSALDRDCISGWGAEVLVLTPEKI
IKKKLKARMD
3D structure
PDB8g6e Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium proteasome inhibitors
ChainX
Resolution2.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YRE X I68 Y71 I67 Y70
BS02 YRE X D138 A142 C144 D130 A134 C136
Gene Ontology
Biological Process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005839 proteasome core complex
GO:0019774 proteasome core complex, beta-subunit complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8g6e, PDBe:8g6e, PDBj:8g6e
PDBsum8g6e
PubMed38097652
UniProtA0A2I0BXS0

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