Structure of PDB 8ewv Chain X

Receptor sequence
>8ewvX (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
TNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGT
IKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQ
KINELPTEE
3D structure
PDB8ewv DNA-encoded library (DEL)-enabled discovery of proximity inducing small molecules
ChainX
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 X5K X F79 W81 P82 F83 Q85 C136 N140 D145 I146 M149 F20 W22 P23 F24 Q26 C77 N81 D86 I87 M90
External links
PDB RCSB:8ewv, PDBe:8ewv, PDBj:8ewv
PDBsum8ewv
PubMed37919549
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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