Structure of PDB 8ekc Chain X

Receptor sequence
>8ekcX (length=94) Species: 562 (Escherichia coli) [Search protein sequence]
MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDHDKVMNM
QAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA
3D structure
PDB8ekc Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin.
ChainX
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna X R9 K14 S17 R21 Y31 Q78 H88 R9 K14 S17 R21 Y31 Q78 H88
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0009314 response to radiation
GO:0017148 negative regulation of translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:8ekc, PDBe:8ekc, PDBj:8ekc
PDBsum8ekc
PubMed36546783
UniProtP68919|RL25_ECOLI Large ribosomal subunit protein bL25 (Gene Name=rplY)

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