Structure of PDB 7tgv Chain X

Receptor sequence
>7tgvX (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGS
TFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMA
NAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGR
TSKKIVITDCGQLS
3D structure
PDB7tgv Discovery and molecular basis of subtype-selective cyclophilin inhibitors.
ChainX
Resolution1.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 I3X X R55 F60 Q63 G72 T73 G74 G75 S81 R82 A101 N102 A103 G109 Q111 F113 W121 H126 R54 F59 Q62 G71 T72 G73 G74 S80 R81 A100 N101 A102 G108 Q110 F112 W120 H125
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:7tgv, PDBe:7tgv, PDBj:7tgv
PDBsum7tgv
PubMed36163383
UniProtP30405|PPIF_HUMAN Peptidyl-prolyl cis-trans isomerase F, mitochondrial (Gene Name=PPIF)

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