Structure of PDB 7tgu Chain X

Receptor sequence
>7tguX (length=163) Species: 9606 (Homo sapiens) [Search protein sequence]
ANPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGS
TFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMA
NAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGR
TSKKIVITDCGQL
3D structure
PDB7tgu Discovery and molecular basis of subtype-selective cyclophilin inhibitors.
ChainX
Resolution1.21 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 I44 X R56 P59 F61 Q64 G73 T74 R83 A102 N103 A104 T108 G110 Q112 F114 H127 R54 P57 F59 Q62 G71 T72 R81 A100 N101 A102 T106 G108 Q110 F112 H125
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:7tgu, PDBe:7tgu, PDBj:7tgu
PDBsum7tgu
PubMed36163383
UniProtP30405|PPIF_HUMAN Peptidyl-prolyl cis-trans isomerase F, mitochondrial (Gene Name=PPIF)

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