Structure of PDB 6r6g Chain X

Receptor sequence

>6r6gX (length=118) Species: 9986 (Oryctolagus cuniculus)

KIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMK
KIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYV
RLAPDYDALDVANKIGII

3D structure

• PDB: 6r6g Structural and mutational analysis of the ribosome-arresting human XBP1u.
• Chain: X
• Resolution: 3.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	X	P44 T45 R47 R48 P49 K50 T51 L52 R53 R56 Q57 Y60 T83 S85 K89 N93 N105 K106 H107 K123 N125 T126 L127 I128 P130 K134 K135 Y137 R139	P6 T7 R9 R10 P11 K12 T13 L14 R15 R18 Q19 Y22 T45 S47 K51 N55 N67 K68 H69 K85 N87 T88 L89 I90 P92 K96 K97 Y99 R101
BS02	rna	X	T51 L52 R55 R56 K63 R67 K70 N105 H107 Q108	T13 L14 R17 R18 K25 R29 K32 N67 H69 Q70

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome

External links

• PDB: RCSB:6r6g, PDBe:6r6g, PDBj:6r6g
• PDBsum: 6r6g
• PubMed: 31246176
• UniProt: G1SE76|RL23A_RABIT Large ribosomal subunit protein uL23 (Gene Name=RPL23A)