Structure of PDB 6px5 Chain X

Receptor sequence
>6px5X (length=140) Species: 9606 (Homo sapiens) [Search protein sequence]
QCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENF
CRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRYQ
TFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYID
3D structure
PDB6px5 Residues W215, E217 and E192 control the allosteric E*-E equilibrium of thrombin.
ChainX
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.5: thrombin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN X E226 E254 E58 E86
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0007596 blood coagulation
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6px5, PDBe:6px5, PDBj:6px5
PDBsum6px5
PubMed31444378
UniProtP00734|THRB_HUMAN Prothrombin (Gene Name=F2)

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