Structure of PDB 6fy2 Chain X

Receptor sequence

>6fy2X (length=219) Species: 9606 (Homo sapiens) [Search protein sequence]

EVQLVQSGAEVKKPGESLKISCKGSGYRFPSSWIGWVRQVPGKGLEWMGI
IYPGDGETRYRASFQGQVTISADQSSNTAYLQWSSLKASDTAMYYCARHG
RGVREVINAFDIWGQGTMVTVSSASTKGPSVFPLAPSGTAALGCLVKDYF
PEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYIC
NVNHKPSNTKVDKKVEPKS

3D structure

PDB

6fy2 Common helical V1V2 conformations of HIV-1 Envelope expose the alpha 4 beta 7 binding site on intact virions.

Chain

Resolution

2.301 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	X	W33 Y52 D54 E56 R58 H95 G96 R97 G98 N100D	W33 Y52 D55 E57 R59 H99 G100 R101 G102 N108

External links

PDB	RCSB:6fy2, PDBe:6fy2, PDBj:6fy2
PDBsum	6fy2
PubMed	30367034

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