Structure of PDB 5lzu Chain X

Receptor sequence

>5lzuX (length=118) Species: 9986 (Oryctolagus cuniculus)

KIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMK
KIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYV
RLAPDYDALDVANKIGII

3D structure

• PDB: 5lzu Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
• Chain: X
• Resolution: 3.75 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	X	P44 T45 R47 R48 P49 K50 T51 L52 R53 R56 Q57 P58 K59 Y60 R62 T83 K89 N93 N105 K106 K123 N125 T126 I128 P130 K134 K135 Y137 R139	P6 T7 R9 R10 P11 K12 T13 L14 R15 R18 Q19 P20 K21 Y22 R24 T45 K51 N55 N67 K68 K85 N87 T88 I90 P92 K96 K97 Y99 R101
BS02	rna	X	F46 P49 T51 L52 R55 R56 P66 R67 R68 N69 K70 H107	F8 P11 T13 L14 R17 R18 P28 R29 R30 N31 K32 H69

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0000027 ribosomal large subunit assembly
• GO:0006412 translation

Cellular Component

• GO:0005634 nucleus
• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:5lzu, PDBe:5lzu, PDBj:5lzu
• PDBsum: 5lzu
• PubMed: 27863242
• UniProt: G1SE76|RL23A_RABIT Large ribosomal subunit protein uL23 (Gene Name=RPL23A)