Structure of PDB 5ezt Chain X

Receptor sequence
>5eztX (length=257) Species: 9913 (Bos taurus) [Search protein sequence]
HWGYGKHNGPEHWHKDFPIANGERQSPVDIDTKAVVQDPALKPLALVYGE
ATSRRMVNNGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQ
GSEHTVDRKKYAAELHLVHWNTKYGDFGTAAQQPDGLAVVGVFLKVGDAN
PALQKVLDALDSIKTKGKSTDFPNFDPGSLLPNVLDYWTYPGSLTTPPLL
ESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPELLMLANWRPAQPLKNR
QVRGFPK
3D structure
PDB5ezt Acetylation of Surface Lysine Groups of a Protein Alters the Organization and Composition of Its Crystal Contacts.
ChainX
Resolution1.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
4.2.1.69: cyanamide hydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN X H93 H95 H118 H91 H93 H116
Gene Ontology
Molecular Function
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
GO:0016829 lyase activity
GO:0018820 cyanamide hydratase activity
GO:0046872 metal ion binding
Biological Process
GO:0006730 one-carbon metabolic process
GO:0015670 carbon dioxide transport
GO:0038166 angiotensin-activated signaling pathway
GO:0044070 regulation of monoatomic anion transport
GO:0051453 regulation of intracellular pH
GO:2001150 positive regulation of dipeptide transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0045177 apical part of cell

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Cellular Component
External links
PDB RCSB:5ezt, PDBe:5ezt, PDBj:5ezt
PDBsum5ezt
PubMed27292012
UniProtP00921|CAH2_BOVIN Carbonic anhydrase 2 (Gene Name=CA2)

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