Structure of PDB 4zo1 Chain X

Receptor sequence
>4zo1X (length=242) Species: 9606 (Homo sapiens) [Search protein sequence]
HKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAVDLEAF
SHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAV
RYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTE
VALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWP
KLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
3D structure
PDB4zo1 Structural mechanism for signal transduction in RXR nuclear receptor heterodimers.
ChainX
Resolution3.221 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide X K288 Q301 I302 E457 K69 Q82 I83 E238
BS02 T3 X F272 I276 R282 R316 L330 N331 G344 H435 F455 F53 I57 R63 R97 L111 N112 G125 H216 F236
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4zo1, PDBe:4zo1, PDBj:4zo1
PDBsum4zo1
PubMed26289479
UniProtP10828|THB_HUMAN Thyroid hormone receptor beta (Gene Name=THRB)

[Back to BioLiP]