Structure of PDB 4kky Chain X

Receptor sequence

>4kkyX (length=411) Species: 303 (Pseudomonas putida)

ETIQSNANLAPLPPHVPEHLVFDFDMYNPSNLSAGVQEAWAVLQESNVPD
LVWTRSNGGHWIATRGQLIREAYEDYRHFSSESPFIPREAGEAYDFIPTS
MDPPEQRQFRCLANQVVGMPVVDKLENRIQELASSLIESLRPQGQCNFTE
DYAEPFPIRIFMLLAGLPEEDIPHLKYLTDQMTRPDGSMTFAEAKEALYD
YLIPIIEQRRQKPGTDAISIVANGQVNGRPITSDEAKRMCGLLLVGGLDT
VVNFLSFSMEFLAKSPEHRQELIERPERIPAASEELLRRFSLVADGRILT
SDYEFHGVQLKKGDQILLPQMLSGLDERENAAPMHVDFSRQKVSHTTFGH
GSHLCLGQHLARREIIVTLKEWLTRIPDFSIAPGAQIQHKSGIVSGVQAL
PLVWDPATTKA

3D structure

• PDB: 4kky To be determined.
• Chain: X
• Resolution: 2.0 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): G248 D251 C357 V396
• Catalytic site (residue number reindexed from 1): G246 D249 C355 V394
• Enzyme Commision number: 1.14.15.1: camphor 5-monooxygenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEM	X	P100 T101 R112 F163 G248 G249 T252 V253 V295 D297 R299 Q322 T349 F350 G351 H355 C357 G359 A363	P98 T99 R110 F161 G246 G247 T250 V251 V293 D295 R297 Q320 T347 F348 G349 H353 C355 G357 A361
BS02	1T4	X	C113 N116	C111 N114
BS03	CAM	X	F87 Y96 L244	F85 Y94 L242

Gene Ontology

Molecular Function

• GO:0004497 monooxygenase activity
• GO:0005506 iron ion binding
• GO:0005515 protein binding
• GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
• GO:0018683 camphor 5-monooxygenase activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding

Biological Process

• GO:0019383 (+)-camphor catabolic process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:4kky, PDBe:4kky, PDBj:4kky
• PDBsum: 4kky
• UniProt: P00183|CPXA_PSEPU Camphor 5-monooxygenase (Gene Name=camC)