Structure of PDB 4j5a Chain X

Receptor sequence
>4j5aX (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGS
TFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMA
NAGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGR
TSKKIVITDCGQLS
3D structure
PDB4j5a Rationnal Design of small-molecule inhibitors of human Cyclophilins and HCV replication.
ChainX
Resolution1.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 67Z X R97 F102 M103 Q105 A143 N144 Q153 F155 L164 H168 R54 F59 M60 Q62 A100 N101 Q110 F112 L121 H125
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:4j5a, PDBe:4j5a, PDBj:4j5a
PDBsum4j5a
PubMed
UniProtP30405|PPIF_HUMAN Peptidyl-prolyl cis-trans isomerase F, mitochondrial (Gene Name=PPIF)

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