Structure of PDB 3pkm Chain X

Receptor sequence
>3pkmX (length=233) Species: 2261 (Pyrococcus furiosus) [Search protein sequence]
HHHHGSRFLIRLVFKVPYNHQYYLQGLIYNAIKSSNPKLATYLHEVKGPK
LFTYSLFMAEKREHPYFLGYKKGFFYFSTCVPEIAEALVNGLLMNPEVRL
WDERFYLHEIKVLREPKKFNGSTFVTLSPIAVTVVRKGKSYDVPPMEKEF
YSIIKDDLQDKYVMAYGDKPPSEFEMEVLIAKPKRFRIKPGIYQTAWHLV
FRAYGNDDLLKVGYEVGFGEKNSLGFGMVKVEG
3D structure
PDB3pkm Interaction of the Cas6 Riboendonuclease with CRISPR RNAs: Recognition and Cleavage.
ChainX
Resolution3.103 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna X R12 Y26 F65 M66 A67 E68 R70 H72 F79 F86 Y153 K194 P195 K196 R197 Y205 T207 H210 V212 E244 R11 Y18 F57 M58 A59 E60 R62 H64 F67 F74 Y141 K182 P183 K184 R185 Y193 T195 H198 V200 E232
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:3pkm, PDBe:3pkm, PDBj:3pkm
PDBsum3pkm
PubMed21300293
UniProtQ8U1S4|CAS6_PYRFU CRISPR-associated endoribonuclease Cas6 (Gene Name=cas6)

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