Structure of PDB 3iqg Chain X

Receptor sequence
>3iqgX (length=310) Species: 727 (Haemophilus influenzae) [Search protein sequence]
AIYADNSYSIGNTPLVRLKHFGHNGNVVVKIEGRNPSYSVKCRIGANMVW
QAEKDGTLTKGKEIVDATSGNTGIALAYVAAARGYKITLTMPETMSLERK
RLLCGLGVNLVLTEGAKGMKGAIAKAEEIVASDPSRYVMLKQFENPANPQ
IHRETTGPEIWKDTDGKVDVVVAGVGTGGSITGISRAIKLDFGKQITSVA
VEPVESPVISQTLAGEEVKPGPHKIQGIGAGFIPKNLDLSIIDRVETVDS
DTALATARRLMAEEGILAGISSGAAVAAADRLAKLPEFADKLIVVILPSA
SERYLSTALF
3D structure
PDB3iqg Design of o-acetylserine sulfhydrylase inhibitors by mimicking nature.
ChainX
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.47: cysteine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide X X42 T69 S70 G71 N72 T73 M120 Q143 G177 G228 A231 F233 X41 T68 S69 G70 N71 T72 M119 Q142 G176 G227 A230 F232
Gene Ontology
Molecular Function
GO:0004124 cysteine synthase activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0080146 L-cysteine desulfhydrase activity
Biological Process
GO:0006535 cysteine biosynthetic process from serine
GO:0019344 cysteine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3iqg, PDBe:3iqg, PDBj:3iqg
PDBsum3iqg
PubMed19928859
UniProtP45040|CYSK_HAEIN Cysteine synthase (Gene Name=cysK)

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