Structure of PDB 3dwo Chain X

Receptor sequence

>3dwoX (length=444) Species: 287 (Pseudomonas aeruginosa)

AGFMVPTTNTAGWGRAMAGGSLFPNDPSAAFNNPAAMAFIDKRIAQLTVN
YADIDIKYNGDAYDYQGNPMTGGYQDGPGTPELGTNDGGQAGFGAWLPTG
FLVVPINDRFAFGLSQVVPMGMRSTWDPNWKGRDFAVDTKIETIGLTGSL
SFKVNDNFSLGAGVIIQRTSGFVSQNLDLYASAANSPGMGGIPFPASNSS
ALMRVKVDNTSPGFFAGAVWKPTDRDTLGFAYHAKIRNKLKGHYNLYDHD
GGLTEGAIEGGTPGLAYPGLDLRMGASASARLDIPAYASLDWVHQFNDRL
SLGASATWTEWSSFQDLTLKSHGNTIVSIPYTYRNTWTLAVGGDYKVTDQ
WTMRAGVAYDQTPTHNATRDPRIPDGDRYFASLGAGYRFQSMPELSIDAA
YSRQFVKEVPLKTVNQDRLGGGRLDGRATSKGQVFSLSATYDFH

3D structure

• PDB: 3dwo Transmembrane passage of hydrophobic compounds through a protein channel wall.
• Chain: X
• Resolution: 2.2 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	C8E	X	Y180 S182 L253 P263 L270 R418	Y180 S182 L253 P263 L270 R418
BS02	C8E	X	I141 V173 V205 L317 Y331 Y333 D370 I373	I141 V173 V205 L317 Y331 Y333 D370 I373
BS03	C8E	X	I54 L97 G121 I373 P374 D375 R378 Q404	I54 L97 G121 I373 P374 D375 R378 Q404
BS04	C8E	X	D377 Y379 F405 K407	D377 Y379 F405 K407
BS05	C8E	X	M353 A355	M353 A355
BS06	C8E	X	T210 S211 P212	T210 S211 P212

Gene Ontology

Molecular Function

• GO:0015483 long-chain fatty acid transporting porin activity

Biological Process

• GO:0015909 long-chain fatty acid transport

Cellular Component

• GO:0016020 membrane

External links

• PDB: RCSB:3dwo, PDBe:3dwo, PDBj:3dwo
• PDBsum: 3dwo
• PubMed: 19182779
• UniProt: Q9HVJ6