Structure of PDB 2qvz Chain X

Receptor sequence
>2qvzX (length=498) Species: 206162 (Alcaligenes sp. AL3007) [Search protein sequence]
MQTVNEMLRRAATRAPDHCALAVPARGLRLTHAELRARVEAVAARLHADG
LRPQQRVAVVAPNSADVVIAILALHRLGAVPALLNPRLKSAELAELIKRG
EMTAAVIAVQVADAIFQSGSGARIIFLGDLVRDGEPYSYGPPIEDPQREP
AQPAFIFYTSGLPKAAIIPQRAAESRVLFMSTQVGLRHGRHNVVLGLMPL
YHVVGFFAVLVAALALDGTYVVVEEFRPVDALQLVQQEQVTSLFATPTHL
DALAAAAAHAGSSLKLDSLRHVTFAGATMPDAVLETVHQHLPGEKVNAYG
TTEAMNSLYMRQPKTGTEMAPGFFSEVRIVRIGGGVDEIVANGEEGELIV
AASDSAFVGYLNQPQATAEKLQDGWYRTSDVAVWTPEGTVRILGRVDDMI
ISGGENIHPSEIERVLGTAPGVTEVVVIGLADQRWGQSVTACVVPRLGET
LSADALDTFCRSSELADFKRPKRYFILDQLPKNALNKVLRRQLVQQVS
3D structure
PDB2qvz Rational redesign of the 4-chlorobenzoate binding site of 4-chlorobenzoate: coenzyme a ligase for expanded substrate range.
ChainX
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.2.1.33: 4-chlorobenzoate--CoA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3BZ X F184 H207 V208 V209 G305 T306 M310 F179 H202 V203 V204 G300 T301 M305
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0016874 ligase activity
GO:0031956 medium-chain fatty acid-CoA ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006631 fatty acid metabolic process
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2qvz, PDBe:2qvz, PDBj:2qvz
PDBsum2qvz
PubMed18027984
UniProtQ8GN86

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