Structure of PDB 2py7 Chain X

Receptor sequence
>2py7X (length=535) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
GLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGYERGVLTNLGAV
AVDTGIFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETWQHL
KGLVTRQLSGKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRP
SDEELAGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGT
WYGGEMKSGMFSMMNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKT
TLSTDPKRRLIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPEIYNAIR
RDALLENVTVREDGTIDFDDGSKTENTRVSYPIYHIDNIVKPVSKAGHAT
KVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLAGTERGITEPTPTF
SACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRISIKDT
RAIIDAILNGSLDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASPEQ
WQEKAETLAKLFIDNFDKYTDTPAGAALVAAGPKL
3D structure
PDB2py7 Crystal structure of E. coli phosphoenolpyruvate carboxykinase mutant Lys213Ser
ChainX
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.1.49: phosphoenolpyruvate carboxykinase (ATP).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN X H232 K254 D269 H227 K249 D264
BS02 MN X D19 H21 D14 H16
BS03 ATP X S250 G251 G253 K254 T255 T256 K288 E297 R333 T441 R449 I450 S451 I452 T455 S245 G246 G248 K249 T250 T251 K283 E292 R328 T436 R444 I445 S446 I447 T450
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004611 phosphoenolpyruvate carboxykinase activity
GO:0004612 phosphoenolpyruvate carboxykinase (ATP) activity
GO:0005509 calcium ion binding
GO:0005524 ATP binding
GO:0016831 carboxy-lyase activity
GO:0017076 purine nucleotide binding
GO:0046872 metal ion binding
Biological Process
GO:0006094 gluconeogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2py7, PDBe:2py7, PDBj:2py7
PDBsum2py7
PubMed
UniProtP22259|PCKA_ECOLI Phosphoenolpyruvate carboxykinase (ATP) (Gene Name=pckA)

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