Structure of PDB 2ijg Chain X

Receptor sequence

>2ijgX (length=492) Species: 3702 (Arabidopsis thaliana)

MNDHIHRVPALTEEEIDSVAIKTFERYALPSKRKGKGVTILWFRNDLRVL
DNDALYKAWSSSDTILPVYCLDPRLFHTTHFFNFPKTGALRGGFLMECLV
DLRKNLMKRGLNLLIRSGKPEEILPSLAKDFGARTVFAHKETCSEEVDVE
RLVNQGLKRVNSTKLELIWGSTMYHKDDLPFDVFDLPDVYTQFRKSVEAK
CSIRSSTRIPLSLGPTPSVDDWGDVPTLEKLGVEPQEVTRGMRFVGGESA
GVGRVFEYFWKKDLLKVYKETRNGMLGPDYSTKFSPWLAFGCISPRFIYE
EVQRYEKERVANNSTYWVLFELIWRDYFRFLSIKCGNSLFHLGGPRNVQG
KWSQDQKLFESWRDAKTGYPLIDANMKELSTTGFMSNRGRQIVCSFLVRD
MGLDWRMGAEWFETCLLDYDPCSNYGNWTYGAGVGNDPREDRYFSIPKQA
QNYDPEGEYVAFWLQQLRRLPKEKRHWPGRLMYMDTVVPLKH

3D structure

• PDB: 2ijg Crystal structure of cryptochrome 3 from Arabidopsis thaliana and its implications for photolyase activity
• Chain: X
• Resolution: 2.1 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	X	Y272 S285 T286 K287 S289 E325 R329 F332 N391 R394 Q395 D422 Y423 D424 S427 N428 N431 W432	Y268 S281 T282 K283 S285 E321 R325 F328 N387 R390 Q391 D418 Y419 D420 S423 N424 N427 W428
BS02	MHF	X	H84 E149 E150 N341 F344 H345 E417 Y423 P425 Y429	H80 E145 E146 N337 F340 H341 E413 Y419 P421 Y425

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0003904 deoxyribodipyrimidine photo-lyase activity
• GO:0003913 DNA photolyase activity
• GO:0005524 ATP binding
• GO:0009881 photoreceptor activity
• GO:0071949 FAD binding

Biological Process

• GO:0000719 photoreactive repair
• GO:0006139 nucleobase-containing compound metabolic process
• GO:0006281 DNA repair

Cellular Component

• GO:0005739 mitochondrion
• GO:0009507 chloroplast

External links

• PDB: RCSB:2ijg, PDBe:2ijg, PDBj:2ijg
• PDBsum: 2ijg
• PubMed: 17101984
• UniProt: Q84KJ5|CRYD_ARATH Cryptochrome DASH, chloroplastic/mitochondrial (Gene Name=CRYD)