Structure of PDB 2aii Chain X

Receptor sequence
>2aiiX (length=274) Species: 9606 (Homo sapiens) [Search protein sequence]
LAHSKMVPIPAGVFTMGTDDPQIKQDGEAPARRVTIDAFYMDAYEVSNTE
FEKFVNSTGYLTEAEKFGDSFVFEGMLAAAPWWLPVKGANWRHPEGPDST
ILHRPDHPVLHVSWNDAVAYCTWAGKRLPTEAEWEYSCRGGLHNRLFPWG
NKLQPKGQHYANIWQGEFPVTNTGEDGFQGTAPVDAFPPNGYGLYNIVGN
AWEWTSDWWTVHHSVEETLNPKGPPSGKDRVKKGGSYMCHRSYCYRYRCA
ARSQNTPDSSASNLGFRCAADRLP
3D structure
PDB2aii A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme
ChainX
Resolution1.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.8.3.7: formylglycine-generating enzyme.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA X E130 N293 I294 G296 A298 E300 E45 N196 I197 G199 A201 E203
BS02 CA X N259 I260 D273 F275 N162 I163 D176 F178
External links
PDB RCSB:2aii, PDBe:2aii, PDBj:2aii
PDBsum2aii
PubMed16368756
UniProtQ8NBK3|SUMF1_HUMAN Formylglycine-generating enzyme (Gene Name=SUMF1)

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