Structure of PDB 1sgf Chain X

Receptor sequence
>1sgfX (length=202) Species: 10090 (Mus musculus) [Search protein sequence]
SQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKDDQHRLV
SKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLP
TEEPKLGSTCLASGTCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSY
TCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETM
AN
3D structure
PDB1sgf Structure of mouse 7S NGF: a complex of nerve growth factor with four binding proteins.
ChainX
Resolution3.15 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) H193 S195 G196
Catalytic site (residue number reindexed from 1) H154 S156 G157
Enzyme Commision number 3.4.21.35: tissue kallikrein.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN X D77 H82 D44 H47
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1sgf, PDBe:1sgf, PDBj:1sgf
PDBsum1sgf
PubMed9351801
UniProtP00757|K1KB4_MOUSE Kallikrein 1-related peptidase-like b4 (Gene Name=Klk1b4)

[Back to BioLiP]