Structure of PDB 1r6b Chain X

Receptor sequence
>1r6bX (length=704) Species: 562 (Escherichia coli) [Search protein sequence]
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVD
LVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGR
NEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGLENFTTNLN
QLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGL
AWRIVQGDVPEVMADCTIYSLDIGAGTKYRGDFEKRFKALLKQLEQDTNS
ILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNI
FEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRA
AVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVV
ARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAG
LGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTV
SRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNILLQV
MDNGTLTDNNGRKADFRNVVLVMTTNAGVRAMEEIKKIFTPEFRNRLDNI
IWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDR
AMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKNELTYGFQ
SAQK
3D structure
PDB1r6b Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone.
ChainX
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG X D520 S522 E565 D490 S492 E535
BS02 ADP X L188 I189 G217 G219 K220 T221 A222 I357 P395 D396 I399 L161 I162 G190 G192 K193 T194 A195 I327 P365 D366 I369
BS03 ADP X F461 G498 V499 G500 K501 T502 E503 A701 F431 G468 V469 G470 K471 T472 E473 A654
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006508 proteolysis
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins
GO:0006979 response to oxidative stress
GO:0034605 cellular response to heat
GO:0043335 protein unfolding
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0009368 endopeptidase Clp complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1r6b, PDBe:1r6b, PDBj:1r6b
PDBsum1r6b
PubMed15037248
UniProtP0ABH9|CLPA_ECOLI ATP-dependent Clp protease ATP-binding subunit ClpA (Gene Name=clpA)

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